Investigator / Platform Research Area Position
Jain, Rakesh Breast cancer brain metastasis Postdoctoral Fellow
Jain, Rakesh Tuberculosis Research Postdoctoral Fellowship in Tuberculosis Granuloma Microenvironment
Jain, Rakesh Glioblastoma Postdoctoral Fellowship in Glioblastoma Microenvironment and Anti-Tumor Immunity
Jain, Rakesh Glioblastoma Postdoctoral Fellow in Brain Tumors and Intravital Microscopy
Jain, Rakesh Pediatric Brain Cancers (medulloblastoma, ependymoma, glioma) Postdoctoral Fellow in pediatric brain tumors
Munn, Lance Tumor metastasis and mechanobiology Postdoctoral Fellow
Duda, Dan Molecular Biology Postdoctoral Fellow
Xu, Lei Clinical Correlative Studies Core Research technologist
Fukumura, Dai Nitric Oxide angiogenesis, and/or intravital Microscopy Postdoctoral Fellows
Huang, Peigen Surgical & Animal Core Gnotobiotic Technologist
Huang, Peigen Surgical & Animal Core Animal Care Assistant

Position: Postdoctoral Fellow

Research Area: Breast cancer brain metastasis

Full/Part Time: Full Time

Investigator: Jain, Rakesh

Date Posted: 2017-01-13

Description: The Steele Laboratory is currently seeking a postdoctoral applicant with expertise in breast cancer cell signaling and microenvironment. The position requires a highly motivated and independent researcher to carry out a project aimed at exploring brain-dependent signaling mechanisms to overcome resistance to targeted therapy andto restore anti-tumor immunity. Please see our recent papers for more information about our focus and experimental setup: 1) Askoxylakis et. al., Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment, JNCI 2015 2) Kodack et. al., Emerging strategies for treating brain metastases from breast cancer, Cancer Cell 2015. Experience in the following technical areas is preferred: molecular and cell biology, biochemistry, flow cytometry and FACS, immunohistochemistry and imaging, and murine models of cancer.

Requirements: Individuals must have a Ph.D. and/or M.D., appropriate research experience, strong organizational, interpersonal, communication, and computer skills and be prepared to work in a dynamic team environment. Applicants with a strong training background and publication track record in brain tumors are highly encouraged to apply. Experience in the following technical areas is preferred: immunohistochemistry, imaging and murine models of cancer. To begin the application process, please e-mail a current CV and statement of purpose to jobs@steele.mgh.harvard.edu

Position: Postdoctoral Fellowship in Tuberculosis Granuloma Microenvironment

Research Area: Tuberculosis Research

Full/Part Time: Full Time

Investigator: Jain, Rakesh

Date Posted: 2017-01-13

Description: The Steele Laboratories are currently seeking postdoctoral applicants with expertise in tuberculosis research with extensive experience in immunohistochemistry and tuberculosis pathology. Experience with image analysis is highly preferred. The postdoctoral fellow will participate in an exciting multidisciplinary project aimed at studying the vasculature and matrix of tuberculosis granulomas. The project is funded by the Bill and Melinda Gates Foundation to Prof. Rakesh Jain, with leading tuberculosis collaborators from the NIH and Rutgers University.

Requirements: Individuals must have a Ph.D. and/or M.D., appropriate research experience, strong organizational, interpersonal, communication, and computer skills and be prepared to work in a dynamic team environment. US citizens and permanent US residents are encouraged to apply. To begin the application process, please e-mail a current CV and statement of purpose tojobs@steele.mgh.harvard.edu

Position: Postdoctoral Fellowship in Glioblastoma Microenvironment and Anti-Tumor Immunity

Research Area: Glioblastoma

Full/Part Time: Full Time

Investigator: Jain, Rakesh

Date Posted: 2017-01-13

Description: The Steele Laboratories are currently seeking postdoctoral applicants with expertise in glioblastoma immunity and microenvironment to explore alternatives to current anti-VEGF treatment and modulation of the associated tumor immune component. Applicants with a strong training background and publication track record in immunology are highly encouraged to apply. Experience in the following technical areas is preferred: molecular and cell biology, flow cytometry and FACS, immunohistochemistry and imaging, and murine models of cancer.

Requirements: Individuals must have a Ph.D. and/or M.D., appropriate research experience, strong organizational, interpersonal, communication, and computer skills and be prepared to work in a dynamic team environment. US citizens and permanent US residents are encouraged to apply. To begin the application process, please e-mail a current CV and statement of purpose to jobs@steele.mgh.harvard.edu

Position: Postdoctoral Fellow in Brain Tumors and Intravital Microscopy

Research Area: Glioblastoma

Full/Part Time: Full Time

Investigator: Jain, Rakesh

Date Posted: 2017-01-13

Description: The Steele Laboratory is currently seeking a postdoctoral applicant with training and research experience in tumor biology to carry out exciting multidisciplinary projects aimed at understanding tumor microenvironment in brain tumors. Expertise in animal studies and intravital imaging are necessary for the study.

Requirements: Individuals must have a Ph.D. and/or M.D., appropriate research experience, strong organizational, interpersonal, communication, and computer skills and be prepared to work in a dynamic team environment. Applicants with a strong training background and publication track record in brain tumors are highly encouraged to apply. Experience in the following technical areas is preferred: immunohistochemistry, imaging and murine models of cancer. To begin the application process, please e-mail a current CV and statement of purpose to jobs@steele.mgh.harvard.edu

Position: Postdoctoral Fellow in pediatric brain tumors

Research Area: Pediatric Brain Cancers (medulloblastoma, ependymoma, glioma)

Full/Part Time: Full Time

Investigator: Jain, Rakesh

Date Posted: 2017-01-13

Description: The Steele Laboratory is currently seeking a postdoctoral applicant with training and research experience in tumor biology to carry out exciting multidisciplinary projects aimed at understanding the tumor micro-environment in pediatric brain tumors. Expertise in molecular biology, immunology, animal study and intra-vital imaging are necessary for the study.

Responsibilities: Individuals must have a Ph.D. and/or M.D., appropriate research experience, strong organizational, interpersonal, communication, and computer skills and be prepared to work in a dynamic team environment. Experience in the following technical areas is preferred: molecular and cell biology, flow cytometry and FACS, immunohistochemistry, imaging and murine models of cancer. To begin the application process, please e-mail a current CV and statement of purpose to jobs@steele.mgh.harvard.edu

Position: Postdoctoral Fellow

Research Area: Tumor metastasis and mechanobiology

Full/Part Time: Full Time

Investigator: Munn, Lance

Date Posted: 2017-01-03

Description: Postdoctoral Research position in the Edwin L. Steele Laboratories at Massachusetts General Hospital. The NIH funded project focuses on cancer metastasis and glycocalyx biology. Applicatnts must have a Ph.D. and/or M.D., appropriate research experience, strong organizational, interpersonal, communication, and computer skills and be prepared to work in a dynamic team environment. Experience with small animal surgery and intravital microscopy preferred. Applicants should send a C.V., career statement and 3 letters of recommendation to: munn@steele.mgh.harvard.edu

Position: Postdoctoral Fellow

Research Area: Molecular Biology

Full/Part Time: Full Time

Investigator: Duda, Dan

Date Posted: 2013-08-28

Description: The Steele Laboratory is currently seeking postdoctoral applicants with expertise in molecular biology and cell biology. The project requires a motivated, independent researcher to carry out a project aimed at understanding the molecular underpinnings of liver cancer progression depending on the etiology, as well as of the differential responses to standard therapies.

Requirements: Applicants should send a CV, career statement and three letters of reference to: Dan G. Duda, DMD, PhD Associate Professor Massachusetts General Hospital & Harvard Medical School 100 Blossom Street, Cox Building 734, Boston, MA 02114 duda@steele.mgh.harvard.edu

Position: Research technologist

Research Area: Clinical Correlative Studies Core

Full/Part Time: Full Time

Investigator: Xu, Lei

Date Posted: 2013-03-05

Description: We are looking for a Research Technologist to join our Clinical Correlative Studies Core at the Edwin L. Steele Laboratory. The Technologist will have the primary responsibility of measuring protein concentration in blood and tissue samples from patients enrolled in clinical trials at the Massachusetts General Hospital.

Requirements: Individuals must have a BSc degree, appropriate research experience, strong organizational, interpersonal, communication, and computer skills and be prepared to work in a dynamic team environment. Previous experience in enzyme-linked immuno-sorbent assay (ELISA), immunohistochemistry, flow cytometry, molecular biology and animal experimentation is preferred. Interested candidates should send a cover letter and resume to:
Lei Xu, M.D, Ph.D.
Edwin L. Steele Laboratory
Massachusetts General Hospital
100 Blossom Street, Cox-7
Boston, MA 02114
E-mail: lei@steele.mgh.harvard.edu

Position: Postdoctoral Fellows

Research Area: Nitric Oxide angiogenesis, and/or intravital Microscopy

Full/Part Time: Full Time

Investigator: Fukumura, Dai

Date Posted: 2013-03-05

Description: The Steele Laboratory is currently seeking postdoctoral applicants with expertise in nitric oxide, angiogenesis, vessel maturation, molecular biology, and/or intravital microscopy. The project requires a motivated, independent researcher to carry out a project aimed at understanding role of nitric oxide in tumor angiogenesis, microcirculation and radiation therapy.

Requirements: Applicants should send a CV, career statement and three letters of reference to:
Dai Fukumura, MD, PhD
Associate Professor
Massachusetts General Hospital & Harvard Medical School
100 Blossom Street, Cox Building 736, Boston, MA 02114
dai@steele.mgh.harvard.edu

Position: Gnotobiotic Technologist

Research Area: Surgical & Animal Core

Full/Part Time: Full Time

Investigator: Huang, Peigen

Date Posted: 2013-03-05

Description: We are looking for a Gnotobiotic Technologist to join our Surgical & Animal Core at Cox-7 Animal Facility, the Edwin L. Steele Laboratory. Cox-7 Animal Facility is a gnotobiotic animal colony operated by the Department of Radiation Oncology at the Massachusetts General Hospital. This unique animal facility allows us to carry out longitudinal tumor physiological studies in immunodeficient and genetically engineered mice. All animals are maintained in defined flora condition with a state of the art gnotobiotic animal handling procedures.

Responsibilities: The Gnotobiotic Technologist has the primary responsibility for the isolator breeding program and is also expected to assist maintenance of gnotobiotic mice and genetically engineered mice breeding colony.

Requirements: Bachelor degree in biology, microbiology, laboratory animal science or related field is required. Knowledge in Bacterology, Virology, and Animal Science are also required.
Individuals should have minimum of 2 years of laboratory experience.
Interested candidates should send a cover latter and resume to:
Peigen Huang, M.D., M.Sc.
Director, Cox-7 Animal Facility
Edwin L. Steele Laboratory
Massachusetts General Hospital
100 Blossom Street , Cox-7
Boston , MA 02114
E-mail: peigen@steele.mgh.harvard.edu

Position: Animal Care Assistant

Research Area: Surgical & Animal Core

Full/Part Time: Full Time

Investigator: Huang, Peigen

Date Posted: 2013-03-05

Description: We are looking for an Animal Care Assistant to join our Surgical & Animal Core at Cox-7 Animal Facility, the Edwin L. Steele Laboratory. Cox-7 Animal Facility is a gnotobiotic animal colony operated by the Department of Radiation Oncology at the MGH. This unique animal facility allows us to carry out longitudinal tumor physiological studies in immunodeficient and genetically engineered mice. All animals are maintained in defined flora condition with a state of the art gnotobiotic animal handling procedures.

Responsibilities: The Animal Care Assistant has the primary responsibility for take good care of the animals, daily maintenance of gnotobiotic mice in the breeding, stock or experimental rooms. The individual is also expected to assist in the preparation of water bottles, cages with bedding, and in washing room; also to help with the general housekeeping sanitation of the facility each day.

Requirements: High school diploma is required. Knowledge in biology and Animal care, with good communication skill are also required.
Individuals should have minimum of 1 year of working experience.
Interested candidates should send a cover latter and resume to:
Peigen Huang, M.D., M.Sc.
Director, Cox-7 Animal Facility
Edwin L. Steele Laboratory
Massachusetts General Hospital
100 Blossom Street , Cox-7
Boston , MA 02114
E-mail: peigen@steele.mgh.harvard.edu

The Massachusetts General Hospital is an Affirmative Action/Equal Opportunity Employer. Applications from women and members of minority groups are encouraged.