Kosuke Kawaguchi
I am a Research Fellow of Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School. I have the expertise, leadership, training, expertise, and motivation necessary to successfully carry out the proposed research project. I have a broad background in breast cancer biology, with specific training and expertise in clinical and translational research in breast cancer.
Linkedin
www.linkedin.com/in/kosuke-kawaguchi-bba1a8145
Other Experience and Professional Memberships
Memberships
2009- American Society of Clinical Oncology
2012- American Association for Cancer Research
2017- Society for Immunotherapy of Cancer
2008- Japan Surgical Society
2008- Japanese Breast Cancer Society
2009- Japanese Society of Medical Oncology
2015- Japanese Society of Clinical Oncology
Board Certification
2012- Board Certified, General Surgeon (Japan, #1002838)
2014- Board Certified, Breast Cancer (Japan, #1281)
Honors
2015: European Society for Medical Oncology (ESMO) Asia 2015 travel grants for the young oncologist
2015: San Antonio Breast Cancer Symposium (SABCS) travel grants for the young oncologist
2016: International Fellowship Grant from Alumni Association of Faculty of Medicine Sanjukai
2016: Japanese Journal of Breast Cancer Award for Excellence Paper
2016: American Society for Clinical Oncology (ASCO) annual meeting 2016 Merit Award
2016: Long-Term Fellowship for Research Abroad from The Kyoto University Foundation
2018: International Fellowship Grant from Kanae Foundation
2018: International Fellowship Grant from Japan Society for the Promotion of Science
Publications
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Ho WW, Gomes-Santos IL, Aoki S, Datta M, Kawaguchi K, Talele NP, Roberge S, Ren J, Liu H, Chen IX, Andersson P, Chatterjee S, Kumar AS, Amoozgar Z, Zhang Q, Huang P, Ng MR, Chauhan VP, Xu L, Duda DG, Clark JW, Pittet MJ, Fukumura D, Jain RK
Dendritic cell paucity in mismatch repair-proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy.
Gomes-Santos IL, Amoozgar Z, Kumar AS, Ho WW, Roh K, Talele NP, Curtis H, Kawaguchi K, Jain RK, Fukumura D
Exercise training improves tumor control by increasing CD8+ T-cell infiltration via CXCR3 signaling and sensitizes breast cancer to immune checkpoint blockade.
Millar DG, Ramjiawan RR, Kawaguchi K, Gupta N, Chen J, Zhang S, Nojiri T, Ho WW, Aoki S, Jung K, Chen I, Shi F, Heather JM, Shigeta K, Morton LT, Sepulveda S, Wan L, Joseph R, Minogue E, Khatri A, Bardia A, Ellisen LW, Corcoran RB, Hata AN, Pai SI, Jain RK, Fukumura D, Duda DG, Cobbold M
Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy.
Incio J, Ligibel JA, McManus DT, Suboj P, Jung K, Kawaguchi K, Pinter M, Babykutty S, Chin SM, Vardam TD, Huang Y, Rahbari NN, Roberge S, Wang D, Gomes-Santos IL, Puchner SB, Schlett CL, Hoffmman U, Ancukiewicz M, Tolaney SM, Krop IE, Duda DG, Boucher Y, Fukumura D, Jain RK
Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2.
Jung K, Heishi T, Incio J, Huang Y, Beech EY, Pinter M, Ho WW, Kawaguchi K, Rahbari NN, Chung E, Kim JK, Clark JW, Willett CG, Yun SH, Luster AD, Padera TP, Jain RK, Fukumura D
Targeting CXCR4-dependent immunosuppressive Ly6C(low) monocytes improves antiangiogenic therapy in colorectal cancer.