Breast cancer can spread—or metastasize—to many different parts of the body, but it’s not well understood why tumors grow better in some organs than others. We explored whether the nutrients available in different tissues help determine where cancer spreads. Using mouse models and advanced metabolic profiling, we measured nutrient levels across several organs and tested how depriving cancer cells of specific nutrients affected their ability to form metastases.

Surprisingly, we found that no single nutrient explains why breast cancer grows in one organ and not another. Instead, a combination of multiple nutrients and cancer cell characteristics work together to determine where tumors can thrive.

See the MGB Research Spotlight HERE

See the article HERE.