Boston Angiogenesis Meeting (BAM) 2024 
 
November 15, 2024; 9:00 AM – 5:00 PM
The Starr Center, 185 Cambridge Street, Boston, MA
 
Meeting Chair: Dan G. Duda, DMD, PhD
Investigator at Mass General Brigham
Professor at Harvard Medical School
 

BAM 2024 Symposium Schedule


9:00 AM – 9:20 AM
Light Breakfast


9:20 AM – 10:50 AM
Latest Trends in Tumor Angiogenesis Research

Chair: Lance L. Munn, PhD

Rakesh K. Jain (MGH)

Special Lecture: "Improving Immunotherapy of Glioblastoma: Emerging Insights and Strategies" (30 min)

Mario Suva (MGH)

"Dissecting Human Gliomas by Single-cell and Spatial Genomics" (20 min)

Diane R. Bielenberg (CHB)

"Neuropilin-2 is Critical to Blood and Lymphatic Vessel Functions" (20 min)

Roger Kamm (MIT)

"Vascularized and perfusable in vitro models for primary and metastatic cancer" (20 min)


 

10:50 AM – 11:10 AM
Coffee Break

11:10 AM – 12:30 PM
Angiogenesis in Non-Malignant Diseases

Chair: Diane R. Bielenberg, PhD

Nathan Lawson (UMass) 

“Dissecting the Developmental Biology of Vascular Anomalies" (20 min)

Patricia D’Amore (Schepens)

"A Role for the Vascular Glycocalyx in Endothelial Biology" (20 min)

Mark W. Feinberg (BWH)

"Turning Trash to Treasure: Targeting Non-coding RNAs for Therapeutic Angiogenesis in Peripheral Artery Disease" (20 min)

Michael Rogers (CHB)

"Why is the Anthrax Toxin Receptor Required for Endothelial Cell Chemotaxis?" (20 min)


12:30 PM – 1:30 PM
Lunch Break


1:30 PM – 2:50 PM
Clinical Translation of Antiangiogenesis

Chair: Dai Fukumura, MD, PhD

Scott Plotkin (MGH)

“Bevacizumab for treatment of NF2-related vestibular schwannomas” (20 min)

Zohreh Amoozgar (MGH)

"Vascular normalization to potentiate immunotherapy in solid tumors" (20 min)

Vincent Xu (DFCI) 

"Anti-angiogenesis Therapies in Renal Cell Carcinoma: Opportunities and Challenges" (20 min)

Mark Leick (MGH)

"Targeted Delivery of a VEGF‐blocking scFv by CAR-T cells" (20 min)


2:50 PM – 3:10 PM
Coffee Break


3:10 PM – 4:50 PM
Open Session: The Future of Angiogenesis Research - "Blitz" talks

Chair: Dan G. Duda, DMD, PhD

Trevor Krolak (HMS)

"Endothelial Gap Junctions Enable Rapid Propagation of Vasodilation During Neurovascular Coupling" (10 min)

Somin Lee (MGH)

“Vessel Normalization Improves EGFRvIII-CAR-T Cell Delivery and Efficacy in Mouse Glioblastoma” (10 min)

Xin Liu  (MGH)

Inhibiting B-cell-mediated Immunosuppression to Enhance the Efficacy of STING Agonism in HCC (10 min)

Tim Dorweiler (CHB)

"Designer Sphingosine-1-Phosphate Chaperones for the Treatment of Diabetic Retinal Disease" (10 min)

Tomofumi Ando  (MGH)

"Treatment-induced Liver-resident NK Cell Activation Is a Therapeutic Target for Achieving Efficacy of Anti-PD-1 Therapy with a VEGFR Kinase Inhibitor in HCC" (10 min)

Keynote lecture:

Tim Padera (MGH)

“Lymphatic Vessel Function in Health and Disease” (45 min)


 

5:00 PM – 6:30 PM
Networking Reception

 


 

SPEAKERS:
 
 
Keynote Speaker: 
 
Timothy P. Padera, PhD
The Rullo Family MGH Research Scholar at Mass General Brigham
Associate Professor at Harvard Medical School
 
Invited Speakers:
 
Rakesh K. Jain, PhD
Director, Steele Laboratories at Mass General Brigham 
Andrew W. Cook Professor of Tumor Biology at Harvard Medical School
 
Patricia D’Amore, PhD, MBA
Director of the Howe Laboratory, Schepens Eye Research Institute
Charles L. Schepens Professor of Ophthalmology and Professor of Pathology at Harvard Medical School
 
Scott Plotkin, MD, PhD
Executive Director, Pappas Center for Neuro-Oncology
Giovanni Armenise Professor of Neurology at Harvard Medical School
 
Michael S. Rogers, PhD
Research Associate, Vascular Biology Program, Boston Children's Hospital
Assistant Professor of Surgery at Harvard Medical School
 
Mark B. Leick, MD
Assistant Professor of Medicine at Harvard Medical School
 
Diane R. Bielenberg, PhD
Research Associate, Vascular Biology Program, Boston Children's Hospital
Assistant Professor of Surgery at Harvard Medical School
 
Nathan Lawson, PhD
Professor of Molecular, Cell, and Cancer Biology
University of Massachusetts Chan Medical School
 
Mark W. Feinberg, MD
Associate Professor of Medicine
Brigham and Women's Hospital and Harvard Medical School
 
Mario L. Suva, MD, PhD
Investigator at Mass General Brigham
Associate Professor of Pathology at Harvard Medical School
 
Zohreh Amoozgar, PharmD, PhD
Scientist at Mass General Brigham
 
Vincent Xu, MD
Physician at Dana Farber Cancer Institute
Assistant Professor of Medicine at Harvard Medical School
 
 
 
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