BAM 2024 Symposium Schedule
9:00 AM – 9:20 AM
Light Breakfast
9:20 AM – 10:50 AM
Latest Trends in Tumor Angiogenesis Research
Chair: Lance L. Munn, PhD
Rakesh K. Jain (MGH)
Special Lecture: "Improving Immunotherapy of Glioblastoma: Emerging Insights and Strategies" (30 min)
Mario Suva (MGH)
"Dissecting Human Gliomas by Single-cell and Spatial Genomics" (20 min)
Diane R. Bielenberg (CHB)
"Neuropilin-2 is Critical to Blood and Lymphatic Vessel Functions" (20 min)
Roger Kamm (MIT)
"Vascularized and perfusable in vitro models for primary and metastatic cancer" (20 min)
10:50 AM – 11:10 AM
Coffee Break
11:10 AM – 12:30 PM
Angiogenesis in Non-Malignant Diseases
Chair: Diane R. Bielenberg, PhD
Nathan Lawson (UMass)
“Dissecting the Developmental Biology of Vascular Anomalies" (20 min)
Patricia D’Amore (Schepens)
"A Role for the Vascular Glycocalyx in Endothelial Biology" (20 min)
Mark W. Feinberg (BWH)
"Turning Trash to Treasure: Targeting Non-coding RNAs for Therapeutic Angiogenesis in Peripheral Artery Disease" (20 min)
Michael Rogers (CHB)
"Why is the Anthrax Toxin Receptor Required for Endothelial Cell Chemotaxis?" (20 min)
12:30 PM – 1:30 PM
Lunch Break
1:30 PM – 2:50 PM
Clinical Translation of Antiangiogenesis
Chair: Dai Fukumura, MD, PhD
Scott Plotkin (MGH)
“Bevacizumab for treatment of NF2-related vestibular schwannomas” (20 min)
Zohreh Amoozgar (MGH)
"Vascular normalization to potentiate immunotherapy in solid tumors" (20 min)
Vincent Xu (DFCI)
"Anti-angiogenesis Therapies in Renal Cell Carcinoma: Opportunities and Challenges" (20 min)
Mark Leick (MGH)
"Targeted Delivery of a VEGF‐blocking scFv by CAR-T cells" (20 min)
2:50 PM – 3:10 PM
Coffee Break
3:10 PM – 4:50 PM
Open Session: The Future of Angiogenesis Research - "Blitz" talks
Chair: Dan G. Duda, DMD, PhD
Trevor Krolak (HMS)
Somin Lee (MGH)
“Vessel Normalization Improves EGFRvIII-CAR-T Cell Delivery and Efficacy in Mouse Glioblastoma” (10 min)
Xin Liu (MGH)
Inhibiting B-cell-mediated Immunosuppression to Enhance the Efficacy of STING Agonism in HCC (10 min)
Tim Dorweiler (CHB)
"Designer Sphingosine-1-Phosphate Chaperones for the Treatment of Diabetic Retinal Disease" (10 min)
Tomofumi Ando (MGH)
"Treatment-induced Liver-resident NK Cell Activation Is a Therapeutic Target for Achieving Efficacy of Anti-PD-1 Therapy with a VEGFR Kinase Inhibitor in HCC" (10 min)
Keynote lecture:
Tim Padera (MGH)
“Lymphatic Vessel Function in Health and Disease” (45 min)
5:00 PM – 6:30 PM
Networking Reception
Giovanni Armenise Professor of Neurology at Harvard Medical School
Assistant Professor of Medicine at Harvard Medical School