Sylvie Roberge
Sylvie Roberge
Publications
HideMutant p53 Exploits Enhancers to Elevate Immunosuppressive Chemokine Expression and Impair Immune Checkpoint Inhibitors in Pancreatic Cancer.
Wnt inhibition alleviates resistance to immune checkpoint blockade in glioblastoma.
Anti-VEGF therapy improves EGFR-vIII-CAR-T cell delivery and efficacy in syngeneic glioblastoma models in mice.
J Immunother Cancer. 2023;11(3):ePub - PMID: 36898734 - PMCID: PMC10008211 - DOI: 10.1136/jitc-2022-005583
Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models.
Proc Natl Acad Sci U S A. 2023;120(6):e2219199120 - PMID: 36724255 - PMCID: PMC9963691 - DOI: 10.1073/pnas.2219199120
Glycocalyx mechanotransduction mechanisms are involved in renal cancer metastasis.
Matrix Biol Plus. 2022;13:100100 - PMID: 35106474 - PMCID: PMC8789524 - DOI: 10.1016/j.mbplus.2021.100100
Dendritic cell paucity in mismatch repair-proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy.
Proc Natl Acad Sci U S A. 2021;118(45):ePub - PMID: 34725151 - PMCID: PMC8609309 - DOI: 10.1073/pnas.2105323118
Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas
Fatty acid synthesis is required for breast cancer brain metastasis
Nature Cancer. 2021;:ePub
In vivo compression and imaging in mouse brain to measure the effects of solid stress.
Nat Protoc. 2020;15(8):2321-2340 - PMID: 32681151 - PMCID: PMC11412114 - DOI: 10.1038/s41596-020-0328-2
A cerebellopontine angle mouse model for the investigation of tumor biology, hearing, and neurological function in NF2-related vestibular schwannoma.
Nat Protoc. 2019;14(2):541-555 - PMID: 30617350 - PMCID: PMC6571021 - DOI: 10.1038/s41596-018-0105-7
Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2.
Sci Transl Med. 2018;10(432):ePub - PMID: 29540614 - PMCID: PMC5936748 - DOI: 10.1126/scitranslmed.aag0945
A cerebellar window for intravital imaging of normal and disease states in mice.
Nat Protoc. 2017;12(11):2251-2262 - PMID: 28981123 - PMCID: PMC5918134 - DOI: 10.1038/nprot.2017.101
An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis.
Quantum dot/antibody conjugates for in vivo cytometric imaging in mice.
Proc Natl Acad Sci U S A. 2015;112(5):1350-5 - PMID: 25605916 - PMCID: PMC4321304 - DOI: 10.1073/pnas.1421632111
Compression of Pancreatic Tumor Blood Vessels by Hyaluronan Is Caused by Solid Stress and Not Interstitial Fluid Pressure.
Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma.
An isolated tumor perfusion model in mice.
BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors.
Cancer Discov. 2011;1(4):352-65 - PMID: 22145099 - PMCID: PMC3229203 - DOI: 10.1158/2159-8290.CD-11-0106
Vascular morphogenesis and remodeling in a model of tissue repair: blood vessel formation and growth in the ovarian pedicle after ovariectomy.
Circ Res. 2001;89(8):723-31 - PMID: 11597996 - DOI: 10.1161/hh2001.097870
Vascular morphogenesis and remodeling in a human tumor xenograft: blood vessel formation and growth after ovariectomy and tumor implantation.
Openings between defective endothelial cells explain tumor vessel leakiness.
Am J Pathol. 2000;156(4):1363-80 - PMID: 10751361 - PMCID: PMC1876882 - DOI: 10.1016/S0002-9440(10)65006-7
Changes in vascularization of human breast cancer xenografts responding to antiestrogen therapy.
Cellular membrane permeability of anthracyclines does not correlate with their delivery in a tissue-isolated tumor.
Cancer Res. 1999;59(17):4458-63 - PMID: 10485498
Effect of tumor necrosis factor alpha on vascular resistance, nitric oxide production, and glucose and oxygen consumption in perfused tissue-isolated human melanoma xenografts.
Clin Cancer Res. 1997;3(3):319-24 - PMID: 10026014
Effect of transvascular fluid exchange on pressure-flow relationship in tumors: a proposed mechanism for tumor blood flow heterogeneity.
Microvasc Res. 1996;52(1):27-46 - PMID: 8812751 - DOI: 10.1006/mvre.1996.0041
Tissue-isolated human tumor xenografts in athymic nude mice.
Microvasc Res. 1994;48(3):389-402 - PMID: 7731400 - DOI: 10.1006/mvre.1994.1063
Transient ultrastructural variations of pulmonary lymphatic capillaries during the respiratory cycle of the rat lung.
Anat Rec. 1985;213(4):551-9 - PMID: 4083535 - DOI: 10.1002/ar.1092130411
Ultrastructural comparative study on lymphatic capillaries of the subendocardium, myocardium, and subepicardium of the heart left ventricle.
Microvasc Res. 1985;29(3):305-19 - PMID: 3999989 - DOI: 10.1016/0026-2862(85)90021-4