Munn Lab

Munn LL, Nia HT

Mechanosensing tensile solid stresses.
Proc Natl Acad Sci U S A. 2019;116(44):21960-21962 - PMID: 31619566 - PMCID: PMC6825278 - DOI: 10.1073/pnas.1916115116

Moran H, Cancel LM, Mayer MA, Qazi H, Munn LL, Tarbell JM

The cancer cell glycocalyx proteoglycan glypican-1 mediates interstitial flow mechanotransduction to enhance cell migration and metastasis.
Biorheology. 2019;56(2-3):151-161 - PMID: 31256115 - DOI: 10.3233/BIR-180203

Seano G, Nia HT, Emblem KE, Datta M, Ren J, Krishnan S, Kloepper J, Pinho MC, Ho WW, Ghosh M, Askoxylakis V, Ferraro GB, Riedemann L, Gerstner ER, Batchelor TT, Wen PY, Lin NU, Grodzinsky AJ, Fukumura D, Huang P, Baish JW, Padera TP, Munn LL, Jain RK

Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium.
Nat Biomed Eng. 2019;3(3):230-245 - PMID: 30948807 - PMCID: PMC6452896 - DOI: 10.1038/s41551-018-0334-7

Nia HT, Munn LL, Jain RK

Mapping physical tumor microenvironment and drug delivery.
Clin Cancer Res. 2019;25(7):2024-2026 - PMID: 30630829 - PMCID: PMC6445672 - DOI: 10.1158/1078-0432.CCR-18-3724
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