Residence time distributions of various tracers in tumors: implications for drug delivery and blood flow measurement.

Physiologically based pharmacokinetic model for specific and nonspecific monoclonal antibodies and fragments in normal tissues and human tumor xenografts in nude mice.

Noninvasive measurement of microvascular and interstitial oxygen profiles in a human tumor in SCID mice.

Barriers to drug delivery in solid tumors.

Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft.

Spatial heterogeneity in tumor perfusion measured with functional computed tomography at 0.05 microliter resolution.

Flow velocity in the superficial lymphatic network of the mouse tail.

A method for labeling cells for positron emission tomography (PET) studies.

Reduction of rigidity in human activated natural killer cells by thioglycollate treatment.

Photodynamic therapy-induced alterations in interstitial fluid pressure, volume and water content of an amelanotic melanoma in the hamster.

Tissue-isolated human tumor xenografts in athymic nude mice.

Angiogenesis and growth of isografted bone: quantitative in vivo assay in nude mice.

Interaction of activated natural killer cells with normal and tumor vessels in cranial windows in mice.

In vivo pharmacokinetics of triazinate in L-1210 and W-256 cells.

Differential response of normal and tumor microcirculation to hyperthermia.

Dielectric properties of solid tumors during normothermia and hyperthermia.

Membrane stability.

Effect of hyperthermia on microvascular permeability to macromolecules in normal and tumor tissues.

Stability of membrane systems modeled as multilayered viscoelastic films.

Effect of glucose and galactose on microcirculatory flow in normal and neoplastic tissues in rabbits.

Effect of glucose and galactose on red blood cell membrane deformability.

Fluorescence ratio imaging of interstitial pH in solid tumours: effect of glucose on spatial and temporal gradients.

Effect of basic fibroblast growth factor on angiogenesis and growth of isografted bone: quantitative in vitro-in vivo analysis in mice.

Transmural coupling of fluid flow in microcirculatory network and interstitium in tumors.

Geometric resistance and microvascular network architecture of human colorectal carcinoma.

The Eugene M. Landis Award Lecture 1996. Delivery of molecular and cellular medicine to solid tumors.

Perfusion of single tumor microvessels: application to vascular permeability measurement.

The problem of chronic rejection: influence of leukocyte-endothelial interactions.

Direct in vivo measurement of targeted binding in a human tumor xenograft.

Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation.

Role of tumor vascular architecture in nutrient and drug delivery: an invasion percolation-based network model.

Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody.

Lateral diffusion of small compounds in human stratum corneum and model lipid bilayer systems.

Extravascular transport in normal and tumor tissues.

1995 Whitaker Lecture: delivery of molecules, particles, and cells to solid tumors.

Heating or freezing bone. Effects on angiogenesis induction and growth potential in mice.

Physiologically based kinetic model of effector cell biodistribution in mammals: implications for adoptive immunotherapy.

Quantitation and physiological characterization of angiogenic vessels in mice: effect of basic fibroblast growth factor, vascular endothelial growth factor/vascular permeability factor, and host microenvironment.

Oxygenation in tumors by modified hemoglobins.

Delivery of molecular medicine to solid tumors.

Quantitative analysis of angiogenesis and growth of bone: effect of indomethacin exposure in a combined in vitro-in vivo approach.

Role of oxygen vs. glucose in energy metabolism in a mammary carcinoma perfused ex vivo: direct measurement by 31P NMR.

Microvascular permeability of albumin, vascular surface area, and vascular volume measured in human adenocarcinoma LS174T using dorsal chamber in SCID mice.

Fluorescence photobleaching with spatial Fourier analysis: measurement of diffusion in light-scattering media.

Inhibition of malignant ascites and growth of human ovarian carcinoma by oral administration of a potent inhibitor of the vascular endothelial growth factor receptor tyrosine kinases.

2H-nuclear magnetic resonance imaging of tumor blood flow: spatial and temporal heterogeneity in a tissue-isolated mammary adenocarcinoma.

Pharmacokinetic analysis of the perivascular distribution of bifunctional antibodies and haptens: comparison with experimental data.

In vitro measurement and screening of monoclonal antibody affinity using fluorescence photobleaching.

Kinetics of interleukin-2 induced changes in rigidity of human natural killer cells.

Pharmacokinetics of methotrexate in leukemia cells: effect of dose and mode of injection.