Transport Barriers Influence the Activation of Anti-Tumor Immunity: A Systems Biology Analysis.
Adv Sci (Weinh). 2023;10(36):e2304076 - PMID: 37949675 - PMCID: PMC10754116 - DOI: 10.1002/advs.202304076
"Isolation and characterization of a novel hormone receptor positive mammary adenocarcinoma MCa-P1362 with stromal drivers of tumor growth, metastasis, and drug resistance".
Cancer cell plasticity and MHC-II-mediated immune tolerance promote breast cancer metastasis to lymph nodes.
Clinical and Prognostic Biomarker Value of Blood Circulating Inflammatory Cytokines in Hepatocellular Carcinoma.
Soluble PD-L1 as a diagnostic and prognostic biomarker in resectable gastric cancer patients.
Gastric Cancer. 2023;26(6):934-946 - PMID: 37668884 - DOI: 10.1007/s10120-023-01429-7
Collagen XVII regulates tumor growth in pancreatic cancer through interaction with the tumor microenvironment.
Scirrhous HCC: Another 'omic thread in the HCC tapestry.
Hepatology. 2023;79(4):747-748 - PMID: 37725712 - DOI: 10.1097/HEP.0000000000000609
Cancer immunotherapy responses persist after lymph node resection.
The Gut Microbiome as a Biomarker and Therapeutic Target in Hepatocellular Carcinoma.
Cancers (Basel). 2023;15(19):ePub - PMID: 37835569 - PMCID: PMC10571776 - DOI: 10.3390/cancers15194875
Desmoplasia in cervical cancer is associated with a more aggressive tumor phenotype.
Computational simulations of tumor growth and treatment response: Benefits of high-frequency, low-dose drug regimens and concurrent vascular normalization.
PLoS Comput Biol. 2023;19(6):e1011131 - PMID: 37289729 - PMCID: PMC10249820 - DOI: 10.1371/journal.pcbi.1011131
Preventing NK cell activation in the damaged liver induced by cabozantinib/PD-1 blockade increases survival in hepatocellular carcinoma models.
Lymphatic muscle cells are unique cells that undergo aging induced changes.
In vivo quantification of programmed death-ligand-1 expression heterogeneity in tumors using fluorescence lifetime imaging.
Mathematical modeling of intratumoral immunotherapy yields strategies to improve the treatment outcomes.
PLoS Comput Biol. 2023;19(12):e1011740 - PMID: 38113269 - PMCID: PMC10763956 - DOI: 10.1371/journal.pcbi.1011740
PPARγ; agonist treatment reduces fibroadipose tissue in secondary lymphedema by exhausting fibroadipogenic PDGFRα+ mesenchymal cells.
JCI Insight. 2023;8(24):ePub - PMID: 38131378 - PMCID: PMC10807713 - DOI: 10.1172/jci.insight.165324
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability.
Experimental and Theoretical Model of Single Vessel Minimally Invasive Micro-Laser Ablation: Inducing Microvascular Network Remodeling and Blood Flow Redistribution Without Compromising Host Tissue Function.
Antigen presentation deficiency, mesenchymal differentiation, and resistance to immunotherapy in the murine syngeneic CT2A tumor model.
Front Immunol. 2023;14:1297932 - PMID: 38213329 - PMCID: PMC10782385 - DOI: 10.3389/fimmu.2023.1297932
Wnt inhibition alleviates resistance to immune checkpoint blockade in glioblastoma.
Mapping the lymphatic system across body scales and expertise domains: A report from the 2021 National Heart, Lung, and Blood Institute workshop at the Boston Lymphatic Symposium.
Front Physiol. 2023;14:1099403 - PMID: 36814475 - PMCID: PMC9939837 - DOI: 10.3389/fphys.2023.1099403
Distinct single-cell immune ecosystems distinguish true and de novo HBV-related hepatocellular carcinoma recurrences.
Gut. 2023;72(6):1196-1210 - PMID: 36596711 - DOI: 10.1136/gutjnl-2022-328428
Mechanistic model for booster doses effectiveness in healthy, cancer, and immunosuppressed patients infected with SARS-CoV-2.
Proc Natl Acad Sci U S A. 2023;120(3):e2211132120 - PMID: 36623200 - PMCID: PMC9934028 - DOI: 10.1073/pnas.2211132120
A new label-free optical imaging method for the lymphatic system enhanced by deep learning.
Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models.
Proc Natl Acad Sci U S A. 2023;120(6):e2219199120 - PMID: 36724255 - PMCID: PMC9963691 - DOI: 10.1073/pnas.2219199120
Proton FLASH effects on mouse skin at different oxygen tensions.
Phys Med Biol. 2023;68(5):ePub - PMID: 36731139 - PMCID: PMC11164666 - DOI: 10.1088/1361-6560/acb888
Predictive Model of Liver Toxicity to Aid the Personalized Selection of Proton vs Photon Therapy in Hepatocellular Carcinoma.
Int J Radiat Oncol Biol Phys. 2023;116(5):1234-1243 - PMID: 36739920 - DOI: 10.1016/j.ijrobp.2023.01.055
Addition of losartan to FOLFIRINOX and chemoradiation reduces immunosuppression-associated genes, Tregs and FOXP3+ cancer cells in locally advanced pancreatic cancer.
Clin Cancer Res. 2023;29(8):1605-1619 - PMID: 36749873 - PMCID: PMC10106451 - DOI: 10.1158/1078-0432.CCR-22-1630
Reprogramming Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy.
Co-Targeting IL-6 and EGFR signaling for the treatment of schwannomatosis and associated pain.
Molecular Mechanisms and Future Implications of VEGF/VEGFR in Cancer Therapy.
Clin Cancer Res. 2023;29(1):30-39 - PMID: 35969170 - PMCID: PMC10274152 - DOI: 10.1158/1078-0432.CCR-22-1366
Inhibition of CXCR4 Enhances the Efficacy of Radiotherapy in Metastatic Prostate Cancer Models.
Cancers (Basel). 2023;15(4):ePub - PMID: 36831366 - PMCID: PMC9954510 - DOI: 10.3390/cancers15041021
Systemic immune modulation by stereotactic radiotherapy in early-stage lung cancer.
NPJ Precis Oncol. 2023;7(1):24 - PMID: 36864234 - PMCID: PMC9981559 - DOI: 10.1038/s41698-023-00358-z
Stressed target cancer cells drive nongenetic reprogramming of CAR T cells and tumor microenvironment, overcoming multiple obstacles of CAR T therapy for solid tumors.
Predicting Severity of Radiation Induced Lymphopenia in Individual Proton Therapy Patients for Varying Dose Rate and Fractionation Using Dynamic 4D Blood Flow Simulations.
Int J Radiat Oncol Biol Phys. 2023;116(5):1226-1233 - PMID: 36739919 - PMCID: PMC10363211 - DOI: 10.1016/j.ijrobp.2023.01.054
Anti-VEGF therapy improves EGFR-vIII-CAR-T cell delivery and efficacy in syngeneic glioblastoma models in mice.
J Immunother Cancer. 2023;11(3):ePub - PMID: 36898734 - PMCID: PMC10008211 - DOI: 10.1136/jitc-2022-005583
Multicenter, prospective, phase 2 study of maintenance bevacizumab for children and adults with NF2-related schwannomatosis and progressive vestibular schwannoma.
Neuro Oncol. 2023;25(8):1498-1506 - PMID: 37010875 - PMCID: PMC10398799 - DOI: 10.1093/neuonc/noad066
Endothelial mechanobiology in atherosclerosis.
Cardiovasc Res. 2023;119(8):1656-1675 - PMID: 37163659 - PMCID: PMC10325702 - DOI: 10.1093/cvr/cvad076
Absence of Tissue-Sparing Effects in Partial Proton FLASH Irradiation in Murine Intestine.
Cancers (Basel). 2023;15(8):ePub - PMID: 37190197 - PMCID: PMC10137009 - DOI: 10.3390/cancers15082269
A Self-Assembly Method for Creating Vascularized Tumor Explants Using Biomaterials for 3D Culture.
Methods Mol Biol. 2023;2645:211-220 - PMID: 37202621 - PMCID: PMC11110101 - DOI: 10.1007/978-1-0716-3056-3_12
40