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Boucher Y, Kirkwood JM, Opacic D, Desantis M, Jain RK
Interstitial hypertension in superficial metastatic melanomas in humans.
Cancer Res. 1991;51(24):6691-4 - PMID: 1742743
Roh HD, Boucher Y, Kalnicki S, Buchsbaum R, Bloomer WD, Jain RK
Interstitial hypertension in carcinoma of uterine cervix in patients: possible correlation with tumor oxygenation and radiation response.
Cancer Res. 1991;51(24):6695-8 - PMID: 1742744
Kurose I, Miura S, Suematsu M, Serizawa H, Fukumura D, Asako H, Hibi T, Tsuchiya M
Tissue-type plasminogen activator of colonic mucosa in ulcerative colitis. Evidence of endothelium-derived fibrinolytic activation.
Dig Dis Sci. 1992;37(2):307-11 - PMID: 1735352 - DOI: 10.1007/BF01308189
Melder RJ, Kristensen CA, Munn LL, Jain RK
Modulation of A-NK cell rigidity: In vitro characterization and in vivo implications for cell delivery.
Biorheology. 2001;38(2-3):151-9 - PMID: 11381172
Lee I, Boucher Y, Jain RK
Nicotinamide can lower tumor interstitial fluid pressure: mechanistic and therapeutic implications.
Cancer Res. 1992;52(11):3237-40 - PMID: 1534273
Kurose I, Miura S, Fukumura D, Tashiro H, Imaeda H, Shiozaki H, Suematsu M, Nagata H, Sekizuka E, Tsuchiya M
Role of platelet activating factor on the fibrinolytic activation in the pathogenesis of gastric mucosal damage induced by endothelin-1.
Gut. 1992;33(7):868-71 - PMID: 1644323 - PMCID: PMC1379395 - DOI: 10.1136/gut.33.7.868
Shimmura S, Tsubota K, Oguchi Y, Fukumura D, Suematsu M, Tsuchiya M
Oxiradical-dependent photoemission induced by a phacoemulsification probe.
Invest Ophthalmol Vis Sci. 1992;33(10):2904-7 - PMID: 1326494
Liu YY, Miura S, Suzuki H, Kurose I, Fukumura D, Suzuki M, Suematsu M, Tsuchiya M
Quantitative analysis of mesenteric microcirculatory disturbances induced by autonomic nervous irritation.
Keio J Med. 1992;41(3):128-33 - PMID: 1434306 - DOI: 10.2302/kjm.41.128
Boucher Y, Jain RK
Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse.
Cancer Res. 1992;52(18):5110-4 - PMID: 1516068
Suzuki M, Miura S, Suematsu M, Fukumura D, Kurose I, Suzuki H, Kai A, Kudoh Y, Ohashi M, Tsuchiya M
Helicobacter pylori-associated ammonia production enhances neutrophil-dependent gastric mucosal cell injury.
Am J Physiol. 1992;263(5 Pt 1):G719-25 - PMID: 1443147 - DOI: 10.1152/ajpgi.1992.263.5.G719
Less JR, Posner MC, Boucher Y, Borochovitz D, Wolmark N, Jain RK
Interstitial hypertension in human breast and colorectal tumors.
Cancer Res. 1992;52(22):6371-4 - PMID: 1423283
Leunig M, Yuan F, Menger MD, Boucher Y, Goetz AE, Messmer K, Jain RK
Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID mice.
Cancer Res. 1992;52(23):6553-60 - PMID: 1384965
Mizukami T, Garkavtsev I, Beach D, Marr T, Niwa O, Yanagida M
[Genome mapping of Schizosaccharomyces pombe].
Tanpakushitsu Kakusan Koso. 1993;38(3):677-84 - PMID: 8488304
Munn LL, Melder RJ, Jain RK
Role of erythrocytes in leukocyte-endothelial interactions: mathematical model and experimental validation.
Biophys J. 1996;71(1):466-78 - PMID: 8804629 - PMCID: PMC1233497 - DOI: 10.1016/S0006-3495(96)79248-2
Duda DG, Sunamura M, Lozonschi L, Kodama T, Egawa S, Matsumoto G, Shimamura H, Shibuya K, Takeda K, Matsuno S
Direct in vitro evidence and in vivo analysis of the antiangiogenesis effects of interleukin 12.
Cancer Res. 2000;60(4):1111-6 - PMID: 10706132
Motoi F, Sunamura M, Ding L, Duda DG, Yoshida Y, Zhang W, Matsuno S, Hamada H
Effective gene therapy for pancreatic cancer by cytokines mediated by restricted replication-competent adenovirus.
Hum Gene Ther. 2000;11(2):223-35 - PMID: 10680837 - DOI: 10.1089/10430340050015978
Ding L, Sunamura M, Kodama T, Yamauchi J, Duda DG, Shimamura H, Shibuya K, Takeda K, Matsuno S
In vivo evaluation of the early events associated with liver metastasis of circulating cancer cells
Br J Cancer. 2001;85:431-8 - PMID: 11487277 - PMCID: PMC2364062 - DOI: 10.1054/bjoc.2001.1911
Munn LL, Melder RJ, Jain RK
Analysis of cell flux in the parallel plate flow chamber: implications for cell capture studies.
Biophys J. 1994;67(2):889-95 - PMID: 7948702 - PMCID: PMC1225432 - DOI: 10.1016/S0006-3495(94)80550-8
Munn LL, Glacken MW, McIntyre BW, Zygourakis K
Analysis of lymphocyte aggregation using digital image analysis.
J Immunol Methods. 1993;166(1):11-25 - PMID: 8228280 - DOI: 10.1016/0022-1759(93)90324-z
Melder RJ, Munn LL, Yamada S, Ohkubo C, Jain RK
Selectin- and integrin-mediated T-lymphocyte rolling and arrest on TNF-alpha-activated endothelium: augmentation by erythrocytes.
Biophys J. 1995;69(5):2131-8 - PMID: 8580357 - PMCID: PMC1236447 - DOI: 10.1016/S0006-3495(95)80087-1
Munn LL, Koenig GC, Jain RK, Melder RJ
Kinetics of adhesion molecule expression and spatial organization using targeted sampling fluorometry.
Biotechniques. 1995;19(4):622-6, 628-31 - PMID: 8777057
Patan S, Munn LL, Jain RK
Intussusceptive microvascular growth in a human colon adenocarcinoma xenograft: a novel mechanism of tumor angiogenesis.
Microvasc Res. 1996;51(2):260-72 - PMID: 8778579 - DOI: 10.1006/mvre.1996.0025
Melder RJ, Koenig GC, Witwer BP, Safabakhsh N, Munn LL, Jain RK
During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium.
Nat Med. 1996;2(9):992-7 - PMID: 8782456 - DOI: 10.1038/nm0996-992
Mizukami T, Chang WI, Garkavtsev I, Kaplan N, Lombardi D, Matsumoto T, Niwa O, Kounosu A, Yanagida M, Marr TG
A 13 kb resolution cosmid map of the 14 Mb fission yeast genome by nonrandom sequence-tagged site mapping.
Cell. 1993;73(1):121-32 - PMID: 8462095 - DOI: 10.1016/0092-8674(93)90165-m
Melder RJ, Koenig GC, Munn LL, Jain RK
Adhesion of activated natural killer cells to tumor necrosis factor-alpha-treated endothelium under physiological flow conditions.
Nat Immun. 1997;15(2-3):154-63 - PMID: 9162265
Shioda T, Munn LL, Fenner MH, Jain RK, Isselbacher KJ
Early events of metastasis in the microcirculation involve changes in gene expression of cancer cells. Tracking mRNA levels of metastasizing cancer cells in the chick embryo chorioallantoic membrane.
Am J Pathol. 1997;150(6):2099-112 - PMID: 9176401 - PMCID: PMC1858325
Lichtenbeld HC, Ferarra N, Jain RK, Munn LL
Effect of local anti-VEGF antibody treatment on tumor microvessel permeability.
Microvasc Res. 1999;57(3):357-62 - PMID: 10329263 - DOI: 10.1006/mvre.1998.2140
Jain RK, Munn LL
Leaky vessels? Call Ang1!
Nat Med. 2000;6(2):131-2 - PMID: 10655092 - DOI: 10.1038/72212
Chang YS, Munn LL, Hillsley MV, Dull RO, Yuan J, Lakshminarayanan S, Gardner TW, Jain RK, Tarbell JM
Effect of vascular endothelial growth factor on cultured endothelial cell monolayer transport properties.
Microvasc Res. 2000;59(2):265-77 - PMID: 10684732 - DOI: 10.1006/mvre.1999.2225
Melder RJ, Yuan J, Munn LL, Jain RK
Erythrocytes enhance lymphocyte rolling and arrest in vivo.
Microvasc Res. 2000;59(2):316-22 - PMID: 10684738 - DOI: 10.1006/mvre.1999.2223
Chang YS, di Tomaso E, McDonald DM, Jones R, Jain RK, Munn LL
Mosaic blood vessels in tumors: frequency of cancer cells in contact with flowing blood.
Proc Natl Acad Sci U S A. 2000;97(26):14608-13 - PMID: 11121063 - PMCID: PMC18966 - DOI: 10.1073/pnas.97.26.14608
Yuan J, Melder RJ, Jain RK, Munn LL
Lateral view flow system for studies of cell adhesion and deformation under flow conditions.
Biotechniques. 2001;30(2):388-94 - PMID: 11233608 - PMCID: PMC2752719 - DOI: 10.2144/01302rr02
Dull RO, Yuan J, Chang YS, Tarbell J, Jain RK, Munn LL
Kinetics of placenta growth factor/vascular endothelial growth factor synergy in endothelial hydraulic conductivity and proliferation.
Microvasc Res. 2001;61(2):203-10 - PMID: 11254400 - DOI: 10.1006/mvre.2000.2298
Kurose I, Miura S, Saito H, Tada S, Fukumura D, Higuchi H, Ishii H
Rat Kupffer cell-derived nitric oxide modulates induction of lymphokine-activated killer cell.
Gastroenterology. 1995;109(6):1958-68 - PMID: 7498662 - DOI: 10.1016/0016-5085(95)90764-5
Atadja P, Wong H, Garkavtsev I, Veillette C, Riabowol K
Increased activity of p53 in senescing fibroblasts.
Proc Natl Acad Sci U S A. 1995;92(18):8348-52 - PMID: 7667293 - PMCID: PMC41154 - DOI: 10.1073/pnas.92.18.8348
Yuan F, Dellian M, Fukumura D, Leunig M, Berk DA, Torchilin VP, Jain RK
Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size.
Cancer Res. 1995;55(17):3752-6 - PMID: 7641188
Boucher Y, Lee I, Jain RK
Lack of general correlation between interstitial fluid pressure and oxygen partial pressure in solid tumors.
Microvasc Res. 1995;50(2):175-82 - PMID: 8538498 - DOI: 10.1006/mvre.1995.1051
Miura S, Tsuzuki Y, Fukumura D, Serizawa H, Suematsu M, Kurose I, Imaeda H, Kimura H, Nagata H, Tsuchiya M
Intravital demonstration of sequential migration process of lymphocyte subpopulations in rat Peyer's patches.
Gastroenterology. 1995;109(4):1113-23 - PMID: 7557076 - DOI: 10.1016/0016-5085(95)90569-3
Fukumura D, Kurose I, Miura S, Tsuchiya M, Ishii H
Oxidative stress in gastric mucosal injury: role of platelet-activating factor-activated granulocytes.
J Gastroenterol. 1995;30(5):565-71 - PMID: 8574326 - DOI: 10.1007/BF02367780
Fukumura D, Salehi HA, Witwer B, Tuma RF, Melder RJ, Jain RK
Tumor necrosis factor alpha-induced leukocyte adhesion in normal and tumor vessels: effect of tumor type, transplantation site, and host strain.
Cancer Res. 1995;55(21):4824-9 - PMID: 7585514
Miura S, Fukumura D, Shiozaki H, Suzuki M, Kurose I, Suematsu M, Tsuchiya M, Ishii H
Bile acid-induced depolarization of mitochondrial membrane potential preceding cell injury in cultured gastric mucosal cells.
J Gastroenterol Hepatol. 1996;10(6):621-6 - PMID: 8580403 - DOI: 10.1111/j.1440-1746.1995.tb01360.x
Zlotecki RA, Baxter LT, Boucher Y, Jain RK
Pharmacologic modification of tumor blood flow and interstitial fluid pressure in a human tumor xenograft: network analysis and mechanistic interpretation.
Microvasc Res. 1995;50(3):429-43 - PMID: 8583955 - DOI: 10.1006/mvre.1995.1069
Netti PA, Baxter LT, Boucher Y, Skalak R, Jain RK
Time-dependent behavior of interstitial fluid pressure in solid tumors: implications for drug delivery.
Cancer Res. 1995;55(22):5451-8 - PMID: 7585615
Yoshida M, Fukumura D, Wakabayashi G, Otani Y, Oshima A, Shimazu M, Kubota T, Kumai K, Kurose I, Miura S
Gastric microcirculatory disturbance and behaviour of leucocytes after thermal injury: intravital observation of arteriovenous shunting channels in the gastric submucosal layer.
J Gastroenterol Hepatol. 1996;10(4):365-70 - PMID: 8527699 - DOI: 10.1111/j.1440-1746.1995.tb01585.x
Suzuki H, Miura S, Imaeda H, Suzuki M, Han JY, Mori M, Fukumura D, Tsuchiya M, Ishii H
Enhanced levels of chemiluminescence and platelet activating factor in urease-positive gastric ulcers.
Free Radic Biol Med. 1996;20(3):449-54 - PMID: 8720917 - DOI: 10.1016/0891-5849(96)02048-5
Suzuki M, Mori M, Miura S, Suematsu M, Fukumura D, Kimura H, Ishii H
Omeprazole attenuates oxygen-derived free radical production from human neutrophils.
Free Radic Biol Med. 1997;21(5):727-31 - PMID: 8891677 - DOI: 10.1016/0891-5849(96)00180-3
Znati CA, Rosenstein M, Boucher Y, Epperly MW, Bloomer WD, Jain RK
Effect of radiation on interstitial fluid pressure and oxygenation in a human tumor xenograft.
Cancer Res. 1996;56(5):964-68 - PMID: 8640786
Fukumura D, Kurose I, Miura S, Serizawa H, Sekizuka E, Nagata H, Tsuchiya M, Ishii H
Role of endothelin-1 in repeated electrical stimulation-induced microcirculatory disturbance and mucosal damage in rat stomach.
J Gastroenterol Hepatol. 1996;11(3):279-85 - PMID: 8742927 - DOI: 10.1111/j.1440-1746.1996.tb00076.x
Jain RK, Koenig GC, Dellian M, Fukumura D, Munn LL, Melder RJ
Leukocyte-endothelial adhesion and angiogenesis in tumors.
Cancer Metastasis Rev. 1996;15(2):195-204 - PMID: 8842491 - DOI: 10.1007/BF00437472
Fukumura D, Yonei Y, Kurose I, Saito H, Ohishi T, Higuchi H, Miura S, Kato S, Kimura H, Ebinuma H, Ishi H
Role in nitric oxide in Kupffer cell-mediated hepatoma cell cytotoxicity in vitro and ex vivo.
Hepatology. 1996;24(1):141-9 - PMID: 8707254 - DOI: 10.1053/jhep.1996.v24.pm0008707254
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