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Higuchi H, Kurose I, Fukumura D, Yan HJ, Saito H, Miura S, Hokari R, Watanabe N, Zeki S, Yoshida M, Kitajima M, Granger DN, Ishii H
Active oxidants mediate IFN-alpha-induced microvascular alterations in rat mesentery.
J Immunol. 1997;158(10):4893-900 - PMID: 9144506
Fukumura D, Kurose I, Miura S, Tsuchiya M, Ishii H
Oxidative stress in gastric mucosal injury: role of platelet-activating factor-activated granulocytes.
J Gastroenterol. 1995;30(5):565-71 - PMID: 8574326 - DOI: 10.1007/BF02367780
Lee I, Demhartner TJ, Boucher Y, Jain RK, Intaglietta M
Effect of hemodilution and resuscitation on tumor interstitial fluid pressure, blood flow, and oxygenation.
Microvasc Res. 1994;48(1):1-12 - PMID: 7990716 - DOI: 10.1006/mvre.1994.1034
Yuan F, Salehi HA, Boucher Y, Vasthare US, Tuma RF, Jain RK
Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows.
Cancer Res. 1994;54(17):4564-8 - PMID: 8062241
Suzuki M, Miura S, Mori M, Kai A, Suzuki H, Fukumura D, Suematsu M, Tsuchiya M
Rebamipide, a novel antiulcer agent, attenuates Helicobacter pylori induced gastric mucosal cell injury associated with neutrophil derived oxidants.
Gut. 1994;35(10):1375-8 - PMID: 7959190 - PMCID: PMC1375008 - DOI: 10.1136/gut.35.10.1375
Miura S, Fukumura D, Kurose I, Kimura H, Suzuki M, Morishita T, Nagata H, Tsuchiya M, Ishii H
Spatial heterogeneity of mucosal blood flow during ischemia-reperfusion injury of rat stomach investigated by laser Doppler perfusion imaging.
J Gastroenterol. 1995;30(3):279-86 - PMID: 7647892 - DOI: 10.1007/BF02347500
Yoshida M, Fukumura D, Wakabayashi G, Otani Y, Oshima A, Shimazu M, Kubota T, Kumai K, Kurose I, Miura S
Gastric microcirculatory disturbance and behaviour of leucocytes after thermal injury: intravital observation of arteriovenous shunting channels in the gastric submucosal layer.
J Gastroenterol Hepatol. 1996;10(4):365-70 - PMID: 8527699 - DOI: 10.1111/j.1440-1746.1995.tb01585.x
Atadja P, Wong H, Garkavtsev I, Veillette C, Riabowol K
Increased activity of p53 in senescing fibroblasts.
Proc Natl Acad Sci U S A. 1995;92(18):8348-52 - PMID: 7667293 - PMCID: PMC41154 - DOI: 10.1073/pnas.92.18.8348
Yuan F, Dellian M, Fukumura D, Leunig M, Berk DA, Torchilin VP, Jain RK
Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size.
Cancer Res. 1995;55(17):3752-6 - PMID: 7641188
Boucher Y, Lee I, Jain RK
Lack of general correlation between interstitial fluid pressure and oxygen partial pressure in solid tumors.
Microvasc Res. 1995;50(2):175-82 - PMID: 8538498 - DOI: 10.1006/mvre.1995.1051
Miura S, Tsuzuki Y, Fukumura D, Serizawa H, Suematsu M, Kurose I, Imaeda H, Kimura H, Nagata H, Tsuchiya M
Intravital demonstration of sequential migration process of lymphocyte subpopulations in rat Peyer's patches.
Gastroenterology. 1995;109(4):1113-23 - PMID: 7557076 - DOI: 10.1016/0016-5085(95)90569-3
Jeltsch M, Kaipainen A, Joukov V, Meng X, Lakso M, Rauvala H, Swartz M, Fukumura D, Jain RK, Alitalo K
Hyperplasia of lymphatic vessels in VEGF-C transgenic mice.
Science. 1997;276(5317):1423-5 - PMID: 9162011 - DOI: 10.1126/science.276.5317.1423
Fukumura D, Salehi HA, Witwer B, Tuma RF, Melder RJ, Jain RK
Tumor necrosis factor alpha-induced leukocyte adhesion in normal and tumor vessels: effect of tumor type, transplantation site, and host strain.
Cancer Res. 1995;55(21):4824-9 - PMID: 7585514
Miura S, Fukumura D, Shiozaki H, Suzuki M, Kurose I, Suematsu M, Tsuchiya M, Ishii H
Bile acid-induced depolarization of mitochondrial membrane potential preceding cell injury in cultured gastric mucosal cells.
J Gastroenterol Hepatol. 1996;10(6):621-6 - PMID: 8580403 - DOI: 10.1111/j.1440-1746.1995.tb01360.x
Zlotecki RA, Baxter LT, Boucher Y, Jain RK
Pharmacologic modification of tumor blood flow and interstitial fluid pressure in a human tumor xenograft: network analysis and mechanistic interpretation.
Microvasc Res. 1995;50(3):429-43 - PMID: 8583955 - DOI: 10.1006/mvre.1995.1069
Netti PA, Baxter LT, Boucher Y, Skalak R, Jain RK
Time-dependent behavior of interstitial fluid pressure in solid tumors: implications for drug delivery.
Cancer Res. 1995;55(22):5451-8 - PMID: 7585615
Kurose I, Miura S, Saito H, Tada S, Fukumura D, Higuchi H, Ishii H
Rat Kupffer cell-derived nitric oxide modulates induction of lymphokine-activated killer cell.
Gastroenterology. 1995;109(6):1958-68 - PMID: 7498662 - DOI: 10.1016/0016-5085(95)90764-5
Suzuki H, Miura S, Imaeda H, Suzuki M, Han JY, Mori M, Fukumura D, Tsuchiya M, Ishii H
Enhanced levels of chemiluminescence and platelet activating factor in urease-positive gastric ulcers.
Free Radic Biol Med. 1996;20(3):449-54 - PMID: 8720917 - DOI: 10.1016/0891-5849(96)02048-5
Suzuki M, Mori M, Miura S, Suematsu M, Fukumura D, Kimura H, Ishii H
Omeprazole attenuates oxygen-derived free radical production from human neutrophils.
Free Radic Biol Med. 1997;21(5):727-31 - PMID: 8891677 - DOI: 10.1016/0891-5849(96)00180-3
Znati CA, Rosenstein M, Boucher Y, Epperly MW, Bloomer WD, Jain RK
Effect of radiation on interstitial fluid pressure and oxygenation in a human tumor xenograft.
Cancer Res. 1996;56(5):964-68 - PMID: 8640786
Less JR, Skalak TC, Sevick EM, Jain RK
Microvascular architecture in a mammary carcinoma: branching patterns and vessel dimensions.
Cancer Res. 1991;51(1):265-73 - PMID: 1988088
Ohkubo C, Bigos D, Jain RK
Interleukin 2 induced leukocyte adhesion to the normal and tumor microvascular endothelium in vivo and its inhibition by dextran sulfate: implications for vascular leak syndrome.
Cancer Res. 1991;51(5):1561-3 - PMID: 1997196
Sevick EM, Jain RK
Effect of red blood cell rigidity on tumor blood flow: increase in viscous resistance during hyperglycemia.
Cancer Res. 1991;51(10):2727-30 - PMID: 2021951
Yuan F, Baxter LT, Jain RK
Pharmacokinetic analysis of two-step approaches using bifunctional and enzyme-conjugated antibodies.
Cancer Res. 1991;51(12):3119-30 - PMID: 2039991
Baxter LT, Jain RK
Transport of fluid and macromolecules in tumors. II. Role of heterogeneous perfusion and lymphatics.
Microvasc Res. 1990;40(2):246-63 - PMID: 2250603 - DOI: 10.1016/0026-2862(90)90023-k
Jain RK, Stock RJ, Chary SR, Rueter M
Convection and diffusion measurements using fluorescence recovery after photobleaching and video image analysis: in vitro calibration and assessment.
Microvasc Res. 1990;39(1):77-93 - PMID: 2314308 - DOI: 10.1016/0026-2862(90)90060-5
Boucher Y, Baxter LT, Jain RK
Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy.
Cancer Res. 1990;50(15):4478-84 - PMID: 2369726
Gerlowski LE, Jain RK
Microvascular permeability of normal and neoplastic tissues.
Microvasc Res. 1986;31(3):288-305 - PMID: 2423854 - DOI: 10.1016/0026-2862(86)90018-x
Sasaki A, Jain RK, Maghazachi AA, Goldfarb RH, Herberman RB
Low deformability of lymphokine-activated killer cells as a possible determinant of in vivo distribution.
Cancer Res. 1989;49(14):3742-6 - PMID: 2500233
Sevick EM, Jain RK
Viscous resistance to blood flow in solid tumors: effect of hematocrit on intratumor blood viscosity.
Cancer Res. 1989;49(13):3513-9 - PMID: 2731173
Baxter LT, Jain RK
Vascular permeability and interstitial diffusion in superfused tissues: a two-dimensional model.
Microvasc Res. 1988;36(1):108-15 - PMID: 3185299 - DOI: 10.1016/0026-2862(88)90043-x
Jain RK, Baxter LT
Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure.
Cancer Res. 1988;48(24 Pt 1):7022-32 - PMID: 3191477
Sevick EM, Jain RK
Blood flow and venous pH of tissue-isolated Walker 256 carcinoma during hyperglycemia.
Cancer Res. 1988;48(5):1201-7 - PMID: 3342400
DiPette DJ, Ward KA, Jain RK, Kerr NE, Schwarzenberger K
Effect of galactose on systemic hemodynamics and blood flow rate in normal and tumor tissues in rats.
Cancer Res. 1988;48(6):1476-80 - PMID: 3345521
Jain RK
Transport of molecules in the tumor interstitium: a review.
Cancer Res. 1987;47(12):3039-51 - PMID: 3555767
Jain RK, Ward-Hartley KA
Dynamics of cancer cell interactions with microvasculature and interstitium.
Biorheology. 1987;24(2):117-25 - PMID: 3651585 - DOI: 10.3233/bir-1987-24205
DiPette DJ, Ward-Hartley KA, Jain RK
Effect of glucose on systemic hemodynamics and blood flow rate in normal and tumor tissues in rats.
Cancer Res. 1986;46(12 Pt 1):6299-304 - PMID: 3779648
Nugent LJ, Jain RK
Two-compartment model for plasma pharmacokinetics in individual blood vessels.
J Pharmacokinet Biopharm. 1984;12(4):451-61 - PMID: 6084709 - DOI: 10.1007/BF01062668
Nugent LJ, Jain RK
Pore and fiber-matrix models for diffusive transport in normal and neoplastic tissues.
Microvasc Res. 1984;28(2):270-4 - PMID: 6209533 - DOI: 10.1016/0026-2862(84)90022-0
Jain RK, Shah SA, Finney PL
Continuous noninvasive monitoring of pH and temperature in rat Walker 256 carcinoma during normoglycemia and hyperglycemia.
J Natl Cancer Inst. 1984;73(2):429-36 - PMID: 6589435 - DOI: 10.1093/jnci/73.2.429
Jain RK, Weissbrod JM, Wei J
Mass transport in tumors: characterization and applications to chemotherapy.
Adv Cancer Res. 1981;33:251-310 - PMID: 7006335 - DOI: 10.1016/s0065-230x(08)60672-7
Johnson EM, Berk DA, Jain RK, Deen WM
Diffusion and partitioning of proteins in charged agarose gels.
Biophys J. 1995;68(4):1561-8 - PMID: 7787041 - PMCID: PMC1282050 - DOI: 10.1016/S0006-3495(95)80328-0
Neelamegham S, Munn LL, Zygourakis K
A model for the kinetics of homotypic cellular aggregation under static conditions.
Biophys J. 1997;72(1):51-64 - PMID: 8994592 - PMCID: PMC1184296 - DOI: 10.1016/S0006-3495(97)78646-6
Zhu H, Baxter LT, Jain RK
Potential and limitations of radioimmunodetection and radioimmunotherapy with monoclonal antibodies.
J Nucl Med. 1997;38(5):731-41 - PMID: 9170438
Gazit Y, Berk DA, Leunig M, Baxter LT, Jain RK
Scale-invariant behavior and vascular network formation in normal and tumor tissue.
Phys Rev Lett. 1995;75(12):2428-2431 - PMID: 10059301 - DOI: 10.1103/PhysRevLett.75.2428
Pluen A, Netti PA, Jain RK, Berk DA
Diffusion of macromolecules in agarose gels: comparison of linear and globular configurations.
Biophys J. 1999;77(1):542-52 - PMID: 10388779 - PMCID: PMC1300351 - DOI: 10.1016/S0006-3495(99)76911-0
Somasundaran P, Simpson S, Jain RK, Ivanov I, Raghuraman V
Investigation of Thin Aqueous Films on Silica Using a Modified Interferometric Technique.
J Colloid Interface Sci. 2000;225(1):243-246 - PMID: 10767167 - DOI: 10.1006/jcis.2000.6735
Jain RK
Delivery of molecular and cellular medicine to solid tumors.
Adv Drug Deliv Rev. 1997;26(2-3):71-90 - PMID: 10837535 - DOI: 10.1016/s0169-409x(97)00027-6
Kaur A, Hale CL, Ramanujan S, Jain RK, Johnson RP
Differential dynamics of CD4(+) and CD8(+) T-lymphocyte proliferation and activation in acute simian immunodeficiency virus infection.
J Virol. 2000;74(18):8413-24 - PMID: 10954541 - PMCID: PMC116352 - DOI: 10.1128/jvi.74.18.8413-8424.2000
Fukumura D, Gohongi T, Kadambi A, Izumi Y, Ang J, Yun CO, Buerk DG, Huang PL, Jain RK
Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability.
Proc Natl Acad Sci U S A. 2001;98(5):2604-9 - PMID: 11226286 - PMCID: PMC30185 - DOI: 10.1073/pnas.041359198
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